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A Very Early Rehabilitation Trial (AVERT): Phase 1 PDF Print E-mail
Written by Nick   
Thursday, 11 December 2008 05:52

A Very Early Rehabilitation Trial (AVERT): Phase 1

Bernhardt J, Dewey HM, Thrift AG, Donnan GA

Coordinating centre: National Stroke Research Institute

Participating centres: Patients and staff from stroke units at the Austin Hospital, Alfred Hospital, Royal Melbourne Hospital, St. Vincent's Hospital, and Western Hospital Melbourne, Australia.

Background: There is clear evidence that treatment in acute stroke units improves outcome, however, we know little about the components of care responsible for better outcomes.

Aims: To (i) document the level of physical activity in the acute stroke care unit; and (ii) examine the involvement of others on the physical activity of patients.

Study Design: Open observational study of patient activity and therapist report of patient interventions. A survey of stroke unit resources was also undertaken.

Method: Five metropolitan Melbourne stroke units participated. People less than 14 days from stroke onset and receiving an active therapy program were recruited. Ethics approval was obtained from each centre. Open observational behavioral mapping every 10 minutes for two consecutive therapeutic days from 08:00 to 17:00. Up to 25 categories were recorded at each observation period, including people present, location of activity and nature of activity. Treating therapists (physiotherapist, occupational therapists and speech therapists) provided a log of therapy preformed over both observation days. Senior staff completed a survey of stroke unit staffing resources.

Results and discussion can be obtained from publications (see below). The AVERT Phase 1 project was completed in December 2004.

Funding for this project was obtained from an NH&MRC Post Doctoral Fellowship (Julie Bernhardt) and an Austin Hospital Medical Research Fund seeding grant.

The following publications have arisen from this study to date:

  1. Bernhardt J, Dewey HM, Thrift AG, Donnan GA. Inactive and alone: Physical activity in the first 14 days of acute stroke unit care. Stroke. 2004; 35: 1005-1009.
  2. Bernhardt J, Chan J, Nicola I, Collier JM. Little therapy, little physical activity: Rehabilitation within the first 14 days of organised stroke unit care. Journal of Rehabilitation Medicine. In press, accepted 19/04/2006.
 
Acute Stroke PDF Print E-mail
Written by Nick   
Thursday, 11 December 2008 05:51

Acute Stroke

Very Early Rehabilitation (VER) Stroke Research Program

are currently looking for acute stroke centres within Australia and Overseas to participate in AVERT Phase III. To find out more about the trial, please follow the link to A Very Early Rehabilitation Trial (AVERT): Protocol Synopsis Phase 3.

Reducing both the personal and community burden of stroke is a primary driver of the very early rehabilitation research program. Our research program has the largest randomised controlled trial of very early rehabilitation (AVERT) at its core. We aim to establish the efficacy, cost effectiveness and potential mechanisms of very early rehabilitation.

Key development objectives are to

  • Develop successful partnerships with professional organisations, policy makers, consumers, clinicians and researchers to promote real changes to clinical practice based on evidence
  • Become a world-class stroke research program
  • Publish significant research findings in high impact journals
  • Attract and supervise high quality national and international post graduate students
  • Increase capacity for high quality research within nursing and allied health disciplines
  • Develop new technologies for use in clinical research trials

To find out more please follow these links:

Program staff and students
Research opportunities for graduate students
Newsletter – Information for stroke patients and staff involved in AVERT Research Projects 
A multicentre observational study of acute stroke units (AVERT Phase 1) 
Safety and feasibility of very early rehabilitation (AVERT Phase 2) 
A randomised controlled trial of very early rehabilitation (AVERT Phase 3) 
What is very early stroke unit rehabilitation? 
AVERT Online. A web based randomisation and trial management system